Hi, I am working with LIS2DE12 accelerometer, I want detect any new data is updated to temperature and x,y,z axis registers.can any one provide steps for configuration.

You should set bit I1_ZYXDA in CTRL_REG3 register. With this settings the interrupt pin INT1 is triggered when new data are available.

If you can't use INT1 pin you can continuously read ZYXDA bit in STATUS_REG register which give you the same information.