Custom board with STM32G431 behaves weird

I've done a simple board with a STM32G431, the idea is to be a remote control that drives an infrared led. It has 8 buttons and the MCU should sleep until a button is pressed, then transmit the code and sleep again.

Right now I'm just trying to make the led blink. I've set a default project with Cube IDE and I set up the main loop to toggle the led.

It works fine when I'm debugging, but when I disconnect the cable and power it externally the led just stays on.

Here is the code of the main:

/* USER CODE BEGIN Header */
/**
 ******************************************************************************
 * @file : main.c
 * @brief : Main program body
 ******************************************************************************
 * @attention
 *
 * <h2><center>&copy; Copyright (c) 2022 STMicroelectronics.
 * All rights reserved.</center></h2>
 *
 * This software component is licensed by ST under BSD 3-Clause license,
 * the "License"; You may not use this file except in compliance with the
 * License. You may obtain a copy of the License at:
 * opensource.org/licenses/BSD-3-Clause
 *
 ******************************************************************************
 */
/* USER CODE END Header */
 
/* Includes ------------------------------------------------------------------*/
#include "main.h"
 
/* Private includes ----------------------------------------------------------*/
/* USER CODE BEGIN Includes */
 
/* USER CODE END Includes */
 
/* Private typedef -----------------------------------------------------------*/
/* USER CODE BEGIN PTD */
 
/* USER CODE END PTD */
 
/* Private define ------------------------------------------------------------*/
/* USER CODE BEGIN PD */
/* USER CODE END PD */
 
/* Private macro -------------------------------------------------------------*/
/* USER CODE BEGIN PM */
 
/* USER CODE END PM */
 
/* Private variables ---------------------------------------------------------*/
 
/* USER CODE BEGIN PV */
 
/* USER CODE END PV */
 
/* Private function prototypes -----------------------------------------------*/
void SystemClock_Config(void);
static void MX_GPIO_Init(void);
/* USER CODE BEGIN PFP */
 
/* USER CODE END PFP */
 
/* Private user code ---------------------------------------------------------*/
/* USER CODE BEGIN 0 */
void Set_LED(uint8_t val)
{
	HAL_GPIO_WritePin(OUT_LED_GPIO_Port, OUT_LED_Pin, !val);
}
/* USER CODE END 0 */
 
/**
 * @brief The application entry point.
 * @retval int
 */
int main(void)
{
 /* USER CODE BEGIN 1 */
 
 /* USER CODE END 1 */
 
 
 /* MCU Configuration--------------------------------------------------------*/
 
 /* Reset of all peripherals, Initializes the Flash interface and the Systick. */
 HAL_Init();
 
 /* USER CODE BEGIN Init */
 
 /* USER CODE END Init */
 
 /* Configure the system clock */
 SystemClock_Config();
 
 /* USER CODE BEGIN SysInit */
 
 /* USER CODE END SysInit */
 
 /* Initialize all configured peripherals */
 MX_GPIO_Init();
 /* USER CODE BEGIN 2 */
 
 /* USER CODE END 2 */
 
 
 
 /* Infinite loop */
 /* USER CODE BEGIN WHILE */
 while (1)
 {
 /* USER CODE END WHILE */
 
 /* USER CODE BEGIN 3 */
	 HAL_Delay(500);
	 Set_LED(1);
	 HAL_Delay(500);
	 Set_LED(0);
 }
 /* USER CODE END 3 */
}
 
/**
 * @brief System Clock Configuration
 * @retval None
 */
void SystemClock_Config(void)
{
 RCC_OscInitTypeDef RCC_OscInitStruct = {0};
 RCC_ClkInitTypeDef RCC_ClkInitStruct = {0};
 
 /** Configure the main internal regulator output voltage 
 */
 HAL_PWREx_ControlVoltageScaling(PWR_REGULATOR_VOLTAGE_SCALE1);
 /** Initializes the CPU, AHB and APB busses clocks 
 */
 RCC_OscInitStruct.OscillatorType = RCC_OSCILLATORTYPE_HSI;
 RCC_OscInitStruct.HSIState = RCC_HSI_ON;
 RCC_OscInitStruct.HSICalibrationValue = RCC_HSICALIBRATION_DEFAULT;
 RCC_OscInitStruct.PLL.PLLState = RCC_PLL_NONE;
 if (HAL_RCC_OscConfig(&RCC_OscInitStruct) != HAL_OK)
 {
 Error_Handler();
 }
 /** Initializes the CPU, AHB and APB busses clocks 
 */
 RCC_ClkInitStruct.ClockType = RCC_CLOCKTYPE_HCLK|RCC_CLOCKTYPE_SYSCLK
 |RCC_CLOCKTYPE_PCLK1|RCC_CLOCKTYPE_PCLK2;
 RCC_ClkInitStruct.SYSCLKSource = RCC_SYSCLKSOURCE_HSI;
 RCC_ClkInitStruct.AHBCLKDivider = RCC_SYSCLK_DIV1;
 RCC_ClkInitStruct.APB1CLKDivider = RCC_HCLK_DIV1;
 RCC_ClkInitStruct.APB2CLKDivider = RCC_HCLK_DIV1;
 
 if (HAL_RCC_ClockConfig(&RCC_ClkInitStruct, FLASH_LATENCY_0) != HAL_OK)
 {
 Error_Handler();
 }
}
 
/**
 * @brief GPIO Initialization Function
 * @param None
 * @retval None
 */
static void MX_GPIO_Init(void)
{
 GPIO_InitTypeDef GPIO_InitStruct = {0};
 
 /* GPIO Ports Clock Enable */
 __HAL_RCC_GPIOB_CLK_ENABLE();
 
 /*Configure GPIO pin Output Level */
 HAL_GPIO_WritePin(OUT_LED_GPIO_Port, OUT_LED_Pin, GPIO_PIN_RESET);
 
 /*Configure GPIO pin : OUT_LED_Pin */
 GPIO_InitStruct.Pin = OUT_LED_Pin;
 GPIO_InitStruct.Mode = GPIO_MODE_OUTPUT_PP;
 GPIO_InitStruct.Pull = GPIO_NOPULL;
 GPIO_InitStruct.Speed = GPIO_SPEED_FREQ_LOW;
 HAL_GPIO_Init(OUT_LED_GPIO_Port, &GPIO_InitStruct);
 
}
 
/* USER CODE BEGIN 4 */
 
/* USER CODE END 4 */
 
/**
 * @brief This function is executed in case of error occurrence.
 * @retval None
 */
void Error_Handler(void)
{
 /* USER CODE BEGIN Error_Handler_Debug */
 /* User can add his own implementation to report the HAL error return state */
 
 /* USER CODE END Error_Handler_Debug */
}
 
#ifdef USE_FULL_ASSERT
/**
 * @brief Reports the name of the source file and the source line number
 * where the assert_param error has occurred.
 * @param file: pointer to the source file name
 * @param line: assert_param error line source number
 * @retval None
 */
void assert_failed(uint8_t *file, uint32_t line)
{ 
 /* USER CODE BEGIN 6 */
 /* User can add his own implementation to report the file name and line number,
 tex: printf("Wrong parameters value: file %s on line %d\r\n", file, line) */
 /* USER CODE END 6 */
}
#endif /* USE_FULL_ASSERT */
 
/************************ (C) COPYRIGHT STMicroelectronics *****END OF FILE****/

Clock config:

Thank you!